Effect of the application of a mucin-based saliva substitute on the oral microflora of xerostomic patients.
Identifieur interne : 00C314 ( Main/Exploration ); précédent : 00C313; suivant : 00C315Effect of the application of a mucin-based saliva substitute on the oral microflora of xerostomic patients.
Auteurs : A H Weerkamp [Pays-Bas] ; K. Wagner ; A. Vissink ; E J GravenmadeSource :
- Journal of oral pathology [ 0300-9777 ] ; 1987.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Bactéries (), Bactéries (isolement et purification), Bactéries anaérobies (), Bactéries anaérobies (isolement et purification), Bains de bouche (pharmacologie), Humains, Mucines (administration et posologie), Mucines (pharmacologie), Mâchoire partiellement édentée (microbiologie), Mâchoire édentée (microbiologie), Salive artificielle (pharmacologie), Streptococcus (), Streptococcus (isolement et purification), Sujet âgé, Xérostomie (), Xérostomie (microbiologie), Études transversales.
- MESH :
- administration et posologie : Mucines.
- isolement et purification : Bactéries, Bactéries anaérobies, Streptococcus.
- microbiologie : Mâchoire partiellement édentée, Mâchoire édentée, Xérostomie.
- pharmacologie : Bains de bouche, Mucines, Salive artificielle.
- Adulte d'âge moyen, Bactéries, Bactéries anaérobies, Humains, Streptococcus, Sujet âgé, Xérostomie, Études transversales.
English descriptors
- KwdEn :
- Aged, Bacteria (drug effects), Bacteria (isolation & purification), Bacteria, Anaerobic (drug effects), Bacteria, Anaerobic (isolation & purification), Cross-Sectional Studies, Humans, Jaw, Edentulous (microbiology), Jaw, Edentulous, Partially (microbiology), Middle Aged, Mouthwashes (pharmacology), Mucins (administration & dosage), Mucins (pharmacology), Saliva, Artificial (pharmacology), Streptococcus (drug effects), Streptococcus (isolation & purification), Xerostomia (microbiology), Xerostomia (therapy).
- MESH :
- chemical , administration & dosage : Mucins.
- chemical , pharmacology : Mouthwashes, Mucins, Saliva, Artificial.
- drug effects : Bacteria, Bacteria, Anaerobic, Streptococcus.
- isolation & purification : Bacteria, Bacteria, Anaerobic, Streptococcus.
- microbiology : Jaw, Edentulous, Jaw, Edentulous, Partially, Xerostomia.
- therapy : Xerostomia.
- Aged, Cross-Sectional Studies, Humans, Middle Aged.
Abstract
A cross-sectional study among 46 xerostomic patients was carried out to determine the influence of a mucin-based artificial saliva on the microflora of standardized oral washings. Patient and non-xerostomic control groups were formed according to the use of saliva substitute (ad libitum or from an intraoral reservoir) and dentition (dentate, edentulous, full dentures). Only few differences were observed among the subgroups based on dentition within a specified salivary group. However, the total number of microorganisms and the proportions of veillonellae, actinomycetes, streptococci and S. salivarius were significantly reduced in xerostomic patients not using artificial saliva, whereas lactobacilli, Candida and S. mitior were significantly increased compared to the control groups. Ad libitum use of artificial saliva had little effect, but semi-continuous wetting of the oral cavity through an intra-oral reservoir reversed the xerostomia-induced shifts in the indigenous microflora. However, no significant effect was observed on the proportions of lactobacilli and yeasts, leaving a potentially acidogenic flora.
PubMed: 3123626
Affiliations:
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Wagner</name></author><author><name sortKey="Vissink, A" sort="Vissink, A" uniqKey="Vissink A" first="A" last="Vissink">A. Vissink</name></author><author><name sortKey="Gravenmade, E J" sort="Gravenmade, E J" uniqKey="Gravenmade E" first="E J" last="Gravenmade">E J Gravenmade</name></author></analytic><series><title level="j">Journal of oral pathology</title><idno type="ISSN">0300-9777</idno><imprint><date when="1987" type="published">1987</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Bacteria (drug effects)</term><term>Bacteria (isolation & purification)</term><term>Bacteria, Anaerobic (drug effects)</term><term>Bacteria, Anaerobic (isolation & purification)</term><term>Cross-Sectional Studies</term><term>Humans</term><term>Jaw, Edentulous (microbiology)</term><term>Jaw, Edentulous, Partially (microbiology)</term><term>Middle Aged</term><term>Mouthwashes (pharmacology)</term><term>Mucins (administration & dosage)</term><term>Mucins (pharmacology)</term><term>Saliva, Artificial (pharmacology)</term><term>Streptococcus (drug effects)</term><term>Streptococcus (isolation & purification)</term><term>Xerostomia (microbiology)</term><term>Xerostomia (therapy)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Bactéries ()</term><term>Bactéries (isolement et purification)</term><term>Bactéries anaérobies ()</term><term>Bactéries anaérobies (isolement et purification)</term><term>Bains de bouche (pharmacologie)</term><term>Humains</term><term>Mucines (administration et posologie)</term><term>Mucines (pharmacologie)</term><term>Mâchoire partiellement édentée (microbiologie)</term><term>Mâchoire édentée (microbiologie)</term><term>Salive artificielle (pharmacologie)</term><term>Streptococcus ()</term><term>Streptococcus (isolement et purification)</term><term>Sujet âgé</term><term>Xérostomie ()</term><term>Xérostomie (microbiologie)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Mucins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Mouthwashes</term><term>Mucins</term><term>Saliva, Artificial</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Mucines</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Bacteria</term><term>Bacteria, Anaerobic</term><term>Streptococcus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Bacteria</term><term>Bacteria, Anaerobic</term><term>Streptococcus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Bactéries</term><term>Bactéries anaérobies</term><term>Streptococcus</term></keywords><keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Mâchoire partiellement édentée</term><term>Mâchoire édentée</term><term>Xérostomie</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Jaw, Edentulous</term><term>Jaw, Edentulous, Partially</term><term>Xerostomia</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Bains de bouche</term><term>Mucines</term><term>Salive artificielle</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Xerostomia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Cross-Sectional Studies</term><term>Humans</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Bactéries</term><term>Bactéries anaérobies</term><term>Humains</term><term>Streptococcus</term><term>Sujet âgé</term><term>Xérostomie</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A cross-sectional study among 46 xerostomic patients was carried out to determine the influence of a mucin-based artificial saliva on the microflora of standardized oral washings. Patient and non-xerostomic control groups were formed according to the use of saliva substitute (ad libitum or from an intraoral reservoir) and dentition (dentate, edentulous, full dentures). Only few differences were observed among the subgroups based on dentition within a specified salivary group. However, the total number of microorganisms and the proportions of veillonellae, actinomycetes, streptococci and S. salivarius were significantly reduced in xerostomic patients not using artificial saliva, whereas lactobacilli, Candida and S. mitior were significantly increased compared to the control groups. Ad libitum use of artificial saliva had little effect, but semi-continuous wetting of the oral cavity through an intra-oral reservoir reversed the xerostomia-induced shifts in the indigenous microflora. However, no significant effect was observed on the proportions of lactobacilli and yeasts, leaving a potentially acidogenic flora.</div></front></TEI><affiliations><list><country><li>Pays-Bas</li></country><region><li>Groningue (province)</li></region><settlement><li>Groningue (ville)</li></settlement><orgName><li>Université de Groningue</li></orgName></list><tree><noCountry><name sortKey="Gravenmade, E J" sort="Gravenmade, E J" uniqKey="Gravenmade E" first="E J" last="Gravenmade">E J Gravenmade</name><name sortKey="Vissink, A" sort="Vissink, A" uniqKey="Vissink A" first="A" last="Vissink">A. Vissink</name><name sortKey="Wagner, K" sort="Wagner, K" uniqKey="Wagner K" first="K" last="Wagner">K. Wagner</name></noCountry><country name="Pays-Bas"><region name="Groningue (province)"><name sortKey="Weerkamp, A H" sort="Weerkamp, A H" uniqKey="Weerkamp A" first="A H" last="Weerkamp">A H Weerkamp</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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